CASToR  3.2
Tomographic Reconstruction (PET/SPECT/CT)
Public Member Functions | Protected Attributes | Private Member Functions | List of all members
i1TCModel Class Reference

This class implements a 1 compartiment model, to model kinetics of radiotracers such as radiowater. More...

#include <i1TCModel.hh>

Inheritance diagram for i1TCModel:
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Public Member Functions

 i1TCModel ()
 Constructor of i1TCModel. Simply set all data members to default values. More...
 
 ~i1TCModel ()
 Destructor of i1TCModel. More...
 
int CheckSpecificParameters ()
 This function is used to check whether all member variables have been correctly initialized or not. More...
 
int ReadAndCheckConfigurationFileSpecific ()
 This function is used to read options from a configuration file. More...
 
int ReadAndCheckOptionsList (string a_listOptions)
 
int InitializeSpecific ()
 This function is used to initialize parametric images and basis functions. More...
 
void ShowHelpModelSpecific ()
 This function is used to print out specific help about the dynamic model and its options. It is pure virtual so must be implemented by children. More...
 
int EstimateModelParameters (oImageSpace *ap_Image, int a_ite, int a_sset)
 
int EstimateImageWithModel (oImageSpace *ap_Image, int a_ite, int a_sset)
 
 i1TCModel ()
 
 ~i1TCModel ()
 
int CheckSpecificParameters ()
 This function is used to check the parameters of the child functions before initialization if required. More...
 
int ReadAndCheckConfigurationFileSpecific ()
 This function is used to read options from a configuration file.
It is pure virtual so must be implemented by children. More...
 
int ReadAndCheckOptionsList (string a_listOptions)
 
int InitializeSpecific ()
 A private function used to initialize everything specific to the child model. More...
 
void ShowHelpModelSpecific ()
 This function is used to print out specific help about the dynamic model and its options. It is pure virtual so must be implemented by children. More...
 
int EstimateModelParameters (oImageSpace *ap_Image, int a_ite, int a_sset)
 
int EstimateImageWithModel (oImageSpace *ap_Image, int a_ite, int a_sset)
 
- Public Member Functions inherited from vDynamicModel
 vDynamicModel ()
 Constructor of vDynamicModel. Simply set all data members to default values. More...
 
virtual ~vDynamicModel ()
 Destructor of vDynamicModel. More...
 
void SetImageDimensionsAndQuantification (oImageDimensionsAndQuantification *ap_ImageDimensionsAndQuantification)
 
void SetVerbose (int a_verbose)
 
virtual int CheckParameters ()
 This function is used to check parameters after the latter have been all set using Set functions. More...
 
int ReadAndCheckConfigurationFile (string a_fileOptions)
 
int Initialize ()
 A public function used to initialize the dynamic model. More...
 
void ShowHelp ()
 This function is used to print out general help about dynamic models. More...
 
virtual int EstimateModel (oImageSpace *ap_Image, int a_ite, int a_sset)
 
virtual int EstimateImage (oImageSpace *ap_Image, int a_ite, int a_sset)
 
int SaveParametricImages (int a_iteration, int a_subset=-1)
 
virtual int ApplyOutputFOVMaskingOnParametricImages ()
 Mask the outside of the transaxial FOV based on the m_fovOutPercent. More...
 
bool GetAICflag ()
 
bool GetModelBasisFunctionsRequiredFlag ()
 
int GetNbTimeBasisFunctions ()
 
FLTNB ** GetTimeBasisFunctions ()
 
virtual void ComputeOutputParImage ()
 Compute output image using the m2p_parametricImages matrix Store the result in the m2p_outputParImages matrix. More...
 
void SetUseModelInReconstruction (bool a_useModelInReconstruction)
 
int NNLS (FLTNB **A, int m, int n, FLTNB *B, FLTNB *X, FLTNB *rnorm, FLTNB *wp, FLTNB *zzp, int *indexp)
 
 vDynamicModel ()
 
virtual ~vDynamicModel ()
 
void SetImageDimensionsAndQuantification (oImageDimensionsAndQuantification *ap_ImageDimensionsAndQuantification)
 
void SetVerbose (int a_verbose)
 
virtual int CheckParameters ()
 
int ReadAndCheckConfigurationFile (string a_fileOptions)
 
int Initialize ()
 
void ShowHelp ()
 
virtual int EstimateModel (oImageSpace *ap_Image, int a_ite, int a_sset)
 
virtual int EstimateImage (oImageSpace *ap_Image, int a_ite, int a_sset)
 
int SaveParametricImages (int a_iteration, int a_subset=-1)
 
virtual int ApplyOutputFOVMaskingOnParametricImages ()
 
bool GetAICflag ()
 
bool GetModelBasisFunctionsRequiredFlag ()
 
int GetNbTimeBasisFunctions ()
 
FLTNB ** GetTimeBasisFunctions ()
 
virtual void ComputeOutputParImage ()
 
void SetUseModelInReconstruction (bool a_useModelInReconstruction)
 
int NNLS (FLTNB **A, int m, int n, FLTNB *B, FLTNB *X, FLTNB *rnorm, FLTNB *wp, FLTNB *zzp, int *indexp)
 

Protected Attributes

bool m_savePImgFlag
 
int m_OptimisationMethodFlag
 
FLTNB ** m2p_ct
 
FLTNB ** m2p_cti
 
FLTNBmp_w
 
FLTNB *** m3p_nnlsA
 
FLTNB ** m2p_nnlsB
 
FLTNB ** m2p_nnlsMat
 
uint16_t m_nnlsN =3
 
FLTNBmp_parUpperBounds
 
FLTNBmp_parLowerBounds
 
FLTNB m_RRcst
 
bool m_ridgeRegressionFlag
 
FLTNBmp_DT2
 
FLTNBmp_wpoQ
 
FLTNBmp_wpoA
 
FLTNB ** m2p_wpoP
 
FLTNB ** m2p_wpoFD
 
FLTNB ** m2p_wpoBD
 
bool m_intMethodFlag
 
oMatrix ** mp_Y
 
oMatrix ** mp_X
 
oMatrix ** mp_Xt
 
oMatrix ** mp_XtX
 
oMatrix ** mp_LSnum
 
oMatrix ** mp_LSden
 
oMatrix ** mp_Theta
 
oMatrixmp_RRm
 
oMatrixmp_RRw
 
oMatrix ** mp_RRnum
 
FLTNBmp_VaImage
 
- Protected Attributes inherited from vDynamicModel
oImageDimensionsAndQuantificationmp_ID
 
int m_verbose
 
int m_nbTimeBF
 
int m_nbWeightFactors
 
int m_nbModelParam
 
int m_nbRGModelParam
 
int m_nbCGModelParam
 
string m_AICfile
 
oArterialInputCurvemp_ArterialInputCurve
 
FLTNB ** m2p_parametricImages
 
FLTNBmp_blackListedvoxelsImage
 
FLTNB ** m2p_nestedModelTimeBasisFunctions
 
FLTNB ** m2p_outputParImages
 
FLTNB ** m2p_RGParametricImages
 
FLTNB ** m2p_CGParametricImages
 
string m_fileOptions
 
string m_listOptions
 
bool m_checked
 
bool m_initialized
 
bool m_useModelInReconstruction
 
bool m_saveParImageFlag
 
bool m_saveBlacklistedImageMaskFlag
 
bool m_AICfileProvided
 
bool m_ModelSpecificBasisFunctionsRequired
 
bool m_noImageUpdateFlag
 
bool m_noParametersUpdateFlag
 
int m_startIteUpdateFlag
 
FLTNBmp_maskModel
 
INTNB m_nbVoxelsMask
 
FLTNBmp_w
 
FLTNB *** m3p_nnlsA
 
FLTNB ** m2p_nnlsB
 
FLTNB ** m2p_nnlsMat
 
FLTNB ** m2p_nnlsX
 
FLTNB ** m2p_nnlsWp
 
int ** m2p_nnlsIdx
 
uint16_t m_nnlsN =0
 

Private Member Functions

int EstimateModelParametersWithLS (oImageSpace *ap_ImageS)
 
int EstimateModelParametersWithNNLS (oImageSpace *ap_ImageS)
 
int EstimateModelParametersWithBF (oImageSpace *ap_ImageS)
 
int RRLS (uint16_t a_nP, uint16_t a_nT, FLTNB **a2p_model, FLTNB *ap_data, FLTNB *ap_w, FLTNB *ap_result)
 
int LS (uint16_t a_nP, uint16_t a_nT, FLTNB **a2p_model, FLTNB *ap_data, FLTNB *ap_w, FLTNB *ap_result)
 
FLTNB WPOinc (uint32_t a_time, FLTNB tac, FLTNB b_tac, FLTNB bb_tac, FLTNB n_tac)
 
int IntegrateTAC (FLTNB *ap_tac, FLTNB *ap_citac, int a_th)
 
int WPO (FLTNB *ap_tac, FLTNB *ap_citac, int a_th)
 
int Trapz (FLTNB *ap_tac, FLTNB *ap_citac)
 
int EstimateModelParametersWithLS (oImageSpace *ap_ImageS)
 
int EstimateModelParametersWithNNLS (oImageSpace *ap_ImageS)
 
int EstimateModelParametersWithBF (oImageSpace *ap_ImageS)
 
int RRLS (uint16_t a_nP, uint16_t a_nT, FLTNB **a2p_model, FLTNB *ap_data, FLTNB *ap_w, FLTNB *ap_result)
 
int LS (uint16_t a_nP, uint16_t a_nT, FLTNB **a2p_model, FLTNB *ap_data, FLTNB *ap_w, FLTNB *ap_result)
 
FLTNB WPOinc (uint32_t a_time, FLTNB tac, FLTNB b_tac, FLTNB bb_tac, FLTNB n_tac)
 
int IntegrateTAC (FLTNB *ap_tac, FLTNB *ap_citac, int a_th)
 
int WPO (FLTNB *ap_tac, FLTNB *ap_citac, int a_th)
 
int Trapz (FLTNB *ap_tac, FLTNB *ap_citac)
 

Detailed Description

This class implements a 1 compartiment model, to model kinetics of radiotracers such as radiowater.

Definition at line 51 of file code/include/dynamic/i1TCModel.hh.

Constructor & Destructor Documentation

◆ i1TCModel() [1/2]

i1TCModel::i1TCModel ( )

Constructor of i1TCModel. Simply set all data members to default values.

Definition at line 29 of file code/src/dynamic/i1TCModel.cc.

◆ ~i1TCModel() [1/2]

i1TCModel::~i1TCModel ( )

Destructor of i1TCModel.

Definition at line 88 of file code/src/dynamic/i1TCModel.cc.

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◆ i1TCModel() [2/2]

i1TCModel::i1TCModel ( )

◆ ~i1TCModel() [2/2]

i1TCModel::~i1TCModel ( )

Member Function Documentation

◆ CheckSpecificParameters() [1/2]

int i1TCModel::CheckSpecificParameters ( )
virtual

This function is used to check whether all member variables have been correctly initialized or not.

Returns
0 if success, positive value otherwise.

Implements vDynamicModel.

Definition at line 421 of file code/src/dynamic/i1TCModel.cc.

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◆ CheckSpecificParameters() [2/2]

int i1TCModel::CheckSpecificParameters ( )
virtual

This function is used to check the parameters of the child functions before initialization if required.

It could be overloaded by the child if needed. Default implementation is empty and return 0.

Returns
0 if success, other value otherwise.

Implements vDynamicModel.

◆ EstimateImageWithModel() [1/2]

int i1TCModel::EstimateImageWithModel ( oImageSpace ap_Image,
int  a_ite,
int  a_sset 
)
virtual

Implements vDynamicModel.

◆ EstimateImageWithModel() [2/2]

int i1TCModel::EstimateImageWithModel ( oImageSpace ap_Image,
int  a_ite,
int  a_sset 
)
virtual

Implements vDynamicModel.

Definition at line 1703 of file code/src/dynamic/i1TCModel.cc.

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◆ EstimateModelParameters() [1/2]

int i1TCModel::EstimateModelParameters ( oImageSpace ap_Image,
int  a_ite,
int  a_sset 
)
virtual

Implements vDynamicModel.

◆ EstimateModelParameters() [2/2]

int i1TCModel::EstimateModelParameters ( oImageSpace ap_Image,
int  a_ite,
int  a_sset 
)
virtual

Implements vDynamicModel.

Definition at line 864 of file code/src/dynamic/i1TCModel.cc.

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◆ EstimateModelParametersWithBF() [1/2]

int i1TCModel::EstimateModelParametersWithBF ( oImageSpace ap_ImageS)
private

Definition at line 1147 of file code/src/dynamic/i1TCModel.cc.

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◆ EstimateModelParametersWithBF() [2/2]

int i1TCModel::EstimateModelParametersWithBF ( oImageSpace ap_ImageS)
private

◆ EstimateModelParametersWithLS() [1/2]

int i1TCModel::EstimateModelParametersWithLS ( oImageSpace ap_ImageS)
private

Definition at line 1182 of file code/src/dynamic/i1TCModel.cc.

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◆ EstimateModelParametersWithLS() [2/2]

int i1TCModel::EstimateModelParametersWithLS ( oImageSpace ap_ImageS)
private

◆ EstimateModelParametersWithNNLS() [1/2]

int i1TCModel::EstimateModelParametersWithNNLS ( oImageSpace ap_ImageS)
private

Definition at line 968 of file code/src/dynamic/i1TCModel.cc.

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◆ EstimateModelParametersWithNNLS() [2/2]

int i1TCModel::EstimateModelParametersWithNNLS ( oImageSpace ap_ImageS)
private

◆ InitializeSpecific() [1/2]

int i1TCModel::InitializeSpecific ( )
virtual

This function is used to initialize parametric images and basis functions.

Returns
0 if success, other value otherwise.
0 if success, other value otherwise.

Implements vDynamicModel.

Definition at line 484 of file code/src/dynamic/i1TCModel.cc.

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◆ InitializeSpecific() [2/2]

int i1TCModel::InitializeSpecific ( )
virtual

A private function used to initialize everything specific to the child model.

This function is used to initialize everything specific to the model that should be initialized. It is called by the Initialize() function. It is pure virtual so is implemented only by children.

Returns
An integer reflecting the initialization status; 0 if no problem, another value otherwise.

Implements vDynamicModel.

◆ IntegrateTAC() [1/2]

int i1TCModel::IntegrateTAC ( FLTNB ap_tac,
FLTNB ap_citac,
int  a_th 
)
private

Definition at line 1864 of file code/src/dynamic/i1TCModel.cc.

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◆ IntegrateTAC() [2/2]

int i1TCModel::IntegrateTAC ( FLTNB ap_tac,
FLTNB ap_citac,
int  a_th 
)
private

◆ LS() [1/2]

int i1TCModel::LS ( uint16_t  a_nP,
uint16_t  a_nT,
FLTNB **  a2p_model,
FLTNB ap_data,
FLTNB ap_w,
FLTNB ap_result 
)
private

Definition at line 1544 of file code/src/dynamic/i1TCModel.cc.

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◆ LS() [2/2]

int i1TCModel::LS ( uint16_t  a_nP,
uint16_t  a_nT,
FLTNB **  a2p_model,
FLTNB ap_data,
FLTNB ap_w,
FLTNB ap_result 
)
private

◆ ReadAndCheckConfigurationFileSpecific() [1/2]

int i1TCModel::ReadAndCheckConfigurationFileSpecific ( )
virtual

This function is used to read options from a configuration file.

Returns
0 if success, other value otherwise.

Implements vDynamicModel.

Definition at line 282 of file code/src/dynamic/i1TCModel.cc.

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◆ ReadAndCheckConfigurationFileSpecific() [2/2]

int i1TCModel::ReadAndCheckConfigurationFileSpecific ( )
virtual

This function is used to read options from a configuration file.
It is pure virtual so must be implemented by children.

Returns
0 if success, other value otherwise.

Implements vDynamicModel.

◆ ReadAndCheckOptionsList() [1/2]

int i1TCModel::ReadAndCheckOptionsList ( string  a_listOptions)
virtual

Implements vDynamicModel.

◆ ReadAndCheckOptionsList() [2/2]

int i1TCModel::ReadAndCheckOptionsList ( string  a_listOptions)
virtual

Implements vDynamicModel.

Definition at line 396 of file code/src/dynamic/i1TCModel.cc.

◆ RRLS() [1/2]

int i1TCModel::RRLS ( uint16_t  a_nP,
uint16_t  a_nT,
FLTNB **  a2p_model,
FLTNB ap_data,
FLTNB ap_w,
FLTNB ap_result 
)
private

Definition at line 1342 of file code/src/dynamic/i1TCModel.cc.

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◆ RRLS() [2/2]

int i1TCModel::RRLS ( uint16_t  a_nP,
uint16_t  a_nT,
FLTNB **  a2p_model,
FLTNB ap_data,
FLTNB ap_w,
FLTNB ap_result 
)
private

◆ ShowHelpModelSpecific() [1/2]

void i1TCModel::ShowHelpModelSpecific ( )
virtual

This function is used to print out specific help about the dynamic model and its options. It is pure virtual so must be implemented by children.

Implements vDynamicModel.

◆ ShowHelpModelSpecific() [2/2]

void i1TCModel::ShowHelpModelSpecific ( )
virtual

This function is used to print out specific help about the dynamic model and its options. It is pure virtual so must be implemented by children.

Implements vDynamicModel.

Definition at line 179 of file code/src/dynamic/i1TCModel.cc.

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◆ Trapz() [1/2]

int i1TCModel::Trapz ( FLTNB ap_tac,
FLTNB ap_citac 
)
private

◆ Trapz() [2/2]

int i1TCModel::Trapz ( FLTNB ap_tac,
FLTNB ap_citac 
)
private

Definition at line 1956 of file code/src/dynamic/i1TCModel.cc.

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◆ WPO() [1/2]

int i1TCModel::WPO ( FLTNB ap_tac,
FLTNB ap_citac,
int  a_th 
)
private

◆ WPO() [2/2]

int i1TCModel::WPO ( FLTNB ap_tac,
FLTNB ap_citac,
int  a_th 
)
private

Definition at line 1886 of file code/src/dynamic/i1TCModel.cc.

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◆ WPOinc() [1/2]

FLTNB i1TCModel::WPOinc ( uint32_t  a_time,
FLTNB  tac,
FLTNB  b_tac,
FLTNB  bb_tac,
FLTNB  n_tac 
)
private

Definition at line 1812 of file code/src/dynamic/i1TCModel.cc.

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◆ WPOinc() [2/2]

FLTNB i1TCModel::WPOinc ( uint32_t  a_time,
FLTNB  tac,
FLTNB  b_tac,
FLTNB  bb_tac,
FLTNB  n_tac 
)
private

Member Data Documentation

◆ m2p_ct

FLTNB ** i1TCModel::m2p_ct
protected

Vector containing voxel TACs (multithreaded)

Definition at line 265 of file code/include/dynamic/i1TCModel.hh.

◆ m2p_cti

FLTNB ** i1TCModel::m2p_cti
protected

Vector containing the integral of voxel TACs (multithreaded)

Definition at line 266 of file code/include/dynamic/i1TCModel.hh.

◆ m2p_nnlsB

FLTNB ** i1TCModel::m2p_nnlsB
protected

1D vector for NNLS estimation, containing the solution (multithreaded)

Definition at line 269 of file code/include/dynamic/i1TCModel.hh.

◆ m2p_nnlsMat

FLTNB ** i1TCModel::m2p_nnlsMat
protected

1D working vector for NNLS estimation (multithreaded)

Definition at line 270 of file code/include/dynamic/i1TCModel.hh.

◆ m2p_wpoBD

FLTNB ** i1TCModel::m2p_wpoBD
protected

Definition at line 284 of file code/include/dynamic/i1TCModel.hh.

◆ m2p_wpoFD

FLTNB ** i1TCModel::m2p_wpoFD
protected

Definition at line 283 of file code/include/dynamic/i1TCModel.hh.

◆ m2p_wpoP

FLTNB ** i1TCModel::m2p_wpoP
protected

Definition at line 282 of file code/include/dynamic/i1TCModel.hh.

◆ m3p_nnlsA

FLTNB *** i1TCModel::m3p_nnlsA
protected

2D coefficient matrix for NNLS estimation (multithreaded)

Definition at line 268 of file code/include/dynamic/i1TCModel.hh.

◆ m_intMethodFlag

bool i1TCModel::m_intMethodFlag
protected

Flag indicating the method for TACs integral computation (default=true)

Definition at line 285 of file code/include/dynamic/i1TCModel.hh.

◆ m_nnlsN

uint16_t i1TCModel::m_nnlsN =3
protected

Number of parameters in NNLS/LS estimation

Definition at line 271 of file code/include/dynamic/i1TCModel.hh.

◆ m_OptimisationMethodFlag

int i1TCModel::m_OptimisationMethodFlag
protected

Flag containing the optimization method

Definition at line 263 of file code/include/dynamic/i1TCModel.hh.

◆ m_ridgeRegressionFlag

bool i1TCModel::m_ridgeRegressionFlag
protected

Flag indicating if ridge regression is enabled (default=false)

Definition at line 276 of file code/include/dynamic/i1TCModel.hh.

◆ m_RRcst

FLTNB i1TCModel::m_RRcst
protected

Regularization parameter for ridge regression

Definition at line 275 of file code/include/dynamic/i1TCModel.hh.

◆ m_savePImgFlag

bool i1TCModel::m_savePImgFlag
protected

Flag indicating if parametric images should be written on disk (default=true)

Definition at line 262 of file code/include/dynamic/i1TCModel.hh.

◆ mp_DT2

FLTNB * i1TCModel::mp_DT2
protected

Vector containing the half frame time duration (for integral computation)

Definition at line 278 of file code/include/dynamic/i1TCModel.hh.

◆ mp_LSden

oMatrix ** i1TCModel::mp_LSden
protected

Matrix for computation (th)

Definition at line 293 of file code/include/dynamic/i1TCModel.hh.

◆ mp_LSnum

oMatrix ** i1TCModel::mp_LSnum
protected

Matrix for computation (th)

Definition at line 292 of file code/include/dynamic/i1TCModel.hh.

◆ mp_parLowerBounds

FLTNB * i1TCModel::mp_parLowerBounds
protected

Vector containing parameters lower bound

Definition at line 274 of file code/include/dynamic/i1TCModel.hh.

◆ mp_parUpperBounds

FLTNB * i1TCModel::mp_parUpperBounds
protected

Vector containing parameters upper bound

Definition at line 273 of file code/include/dynamic/i1TCModel.hh.

◆ mp_RRm

oMatrix * i1TCModel::mp_RRm
protected

Ridge means

Definition at line 297 of file code/include/dynamic/i1TCModel.hh.

◆ mp_RRnum

oMatrix ** i1TCModel::mp_RRnum
protected

Ridge numerator for computation (th)

Definition at line 299 of file code/include/dynamic/i1TCModel.hh.

◆ mp_RRw

oMatrix * i1TCModel::mp_RRw
protected

Ridge weights

Definition at line 298 of file code/include/dynamic/i1TCModel.hh.

◆ mp_Theta

oMatrix ** i1TCModel::mp_Theta
protected

Estimated parameters Matrix (th)

Definition at line 294 of file code/include/dynamic/i1TCModel.hh.

◆ mp_VaImage

FLTNB * i1TCModel::mp_VaImage
protected

Optional input image containing the blood volume

Definition at line 301 of file code/include/dynamic/i1TCModel.hh.

◆ mp_w

FLTNB * i1TCModel::mp_w
protected

Vector containing the weights for NNLS estimation

Definition at line 267 of file code/include/dynamic/i1TCModel.hh.

◆ mp_wpoA

FLTNB * i1TCModel::mp_wpoA
protected

Definition at line 281 of file code/include/dynamic/i1TCModel.hh.

◆ mp_wpoQ

FLTNB * i1TCModel::mp_wpoQ
protected

Definition at line 280 of file code/include/dynamic/i1TCModel.hh.

◆ mp_X

oMatrix ** i1TCModel::mp_X
protected

Model Matrix (threaded)

Definition at line 289 of file code/include/dynamic/i1TCModel.hh.

◆ mp_Xt

oMatrix ** i1TCModel::mp_Xt
protected

Matrix for computation (th)

Definition at line 290 of file code/include/dynamic/i1TCModel.hh.

◆ mp_XtX

oMatrix ** i1TCModel::mp_XtX
protected

Matrix for computation (th)

Definition at line 291 of file code/include/dynamic/i1TCModel.hh.

◆ mp_Y

oMatrix ** i1TCModel::mp_Y
protected

Data Matrix (threaded)

Definition at line 288 of file code/include/dynamic/i1TCModel.hh.


The documentation for this class was generated from the following files: